Diphtheria vaccine Type | Usage | Precautions | Side Effects

Diphtheria vaccine Type | Usage | Precautions | Side Effects

  • Diphtheria is caused by Corynebacterium diphtheria, a gram-positive bacteria transmitted from person to person via respiratory droplets.
  • Formation of a grayish pseudo-membrane over pharynx and tonsils is the hallmark of C. diphtheria infection. Myocarditis and arrhythmias are potentially life-threatening complications.

Diphtheria Vaccine

  • Diphtheria vaccine is given in combination with tetanus and pertussis vaccines as DTaP, DT, Td, and Tdap.
    See Tetanus immunization for details.
  • Diphtheria anti-toxin (DAT) is used for management and post-exposure prophylaxis of C. diphtheriae.


  • Routine Use:
    see Tetanus Immunization.
  • Diphtheria antitoxin (DAT): DAT is used both for the management of confirmed or probable cases of Diphtheria, and prophylactically after known or expected exposure to toxigenic Corynebacteria. Because the anti-toxin neutralizes unbound toxin only, it should be used as early as possible.