Immunoglobulin A (IgG) – Laboratory Test Ranges | Reference
Immunoglobulin A (IgG) – Reference range
Age | Value IgG, g/L |
---|---|
< 12 months | 3,5 – 11,1 |
12 months – 10 years | 7,3 – 13,5 |
> 10 years | 8,0 – 18,0 |
Increased IgG:
- chronic and recurrent purulent infections (infectious
mononucleosis, tuberculosis, leprosy, etc.); - autoimmune diseases, particularly systemic lupus
erythematosus, rheumatoid arthritis; - chronic liver disease (chronic hepatitis, cirrhosis)
wherein the degree of increase in IgG is correlated with the severity of
disease; - sarcoidosis;
- cystic fibrosis;
- parasitic infestation;
- HIV infection *;
- asymptomatic monoclonal (IgG) gammopathy;
- multiple myeloma (IgG – type);
- chronic granulomatosis.
Decreased IgG:
acquired deficiency:
- tumor lymphatic system, lymphoproliferative
disease; - state after splenectomy;
- loss of protein in the entero-and nephropathy;
- immunosuppressive therapy, cytostatics;
- exposure to ionizing radiation;
- atopic dermatitis and other allergic diseases;
- hereditary muscular dystrophy;
- transient hypogammaglobulinemia or slow
immunological start (IIA syndrome) – infants; - HIV infection *;
- intake dextran, methylprednisolone, preparations of gold (krizanol, auranofin).
congenital deficiency:
- agammaglobulinemia (Bruton’s disease);
- Wiskott-Aldrich syndrome.
* The values of IgG during HIV infection can be detected from a severe immunodeficiency scope to Hyper depending on the clinical condition and the stage of the disease.