Immunoglobulin A (IgG) – Laboratory Test Ranges | Reference

Immunoglobulin A (IgG) – Laboratory Test Ranges | Reference

Immunoglobulin A (IgG) – Reference range

Age Value IgG, g/L
< 12 months 3,5 – 11,1
12 months – 10 years 7,3 – 13,5
> 10 years 8,0 – 18,0

Increased IgG:

  • chronic and recurrent purulent infections (infectious
    mononucleosis, tuberculosis, leprosy, etc.);
  • autoimmune diseases, particularly systemic lupus
    erythematosus, rheumatoid arthritis;
  • chronic liver disease (chronic hepatitis, cirrhosis)
    wherein the degree of increase in IgG is correlated with the severity of
    disease;
  • sarcoidosis;
  • cystic fibrosis;
  • parasitic infestation;
  • HIV infection *;
  • asymptomatic monoclonal (IgG) gammopathy;
  • multiple myeloma (IgG – type);
  • chronic granulomatosis.

Decreased IgG:

acquired deficiency:

  • tumor lymphatic system, lymphoproliferative
    disease;
  • state after splenectomy;
  • loss of protein in the entero-and nephropathy;
  • immunosuppressive therapy, cytostatics;
  • exposure to ionizing radiation;
  • atopic dermatitis and other allergic diseases;
  • hereditary muscular dystrophy;
  • transient hypogammaglobulinemia or slow
    immunological start (IIA syndrome) – infants;
  • HIV infection *;
  • intake dextran, methylprednisolone, preparations of gold (krizanol, auranofin).

congenital deficiency:

  • agammaglobulinemia (Bruton’s disease);
  • Wiskott-Aldrich syndrome.

* The values of IgG during HIV infection can be detected from a severe immunodeficiency scope to Hyper depending on the clinical condition and the stage of the disease.